Strategies for Successful Use of Clozapine: A Practical Guide-Lecture Presentation

Video Transcription

Video Summary

In this video, Dr. Yvonne Yang discusses strategies for successful use of Clozapine, focusing on prescribers who are either new to prescribing the medication or looking to improve their practice. She highlights the underuse of Clozapine in the United States compared to other countries and emphasizes its effectiveness in treating psychosis. <br /><br />Dr. Yang provides a practical guide for prescribing Clozapine, including the initiation, titration, and maintenance treatment. She emphasizes that there are no absolute contraindications for prescribing Clozapine and encourages prescribers to start patients on the medication, addressing other conditions during treatment. She also discusses the baseline checks required before starting Clozapine and the importance of informed consent.<br /><br />Dr. Yang explains the importance of regular monitoring and reporting of ANC (absolute neutrophil count) and provides different options for titration schedules based on patient needs. She also discusses serum level monitoring and the impact of smoking on Clozapine levels.<br /><br />The video also discusses logistical hurdles associated with prescribing Clozapine, and Dr. Yang provides strategies for success in overcoming these hurdles. She suggests finding a pharmacy experienced with Clozapine and enrolling with the Clozapine REMS (Risk Evaluation and Mitigation Strategy) program. Dr. Yang emphasizes the importance of communication between prescribers, patients, laboratories, and pharmacies to ensure smooth coordination of care.<br /><br />Overall, the video provides valuable information for prescribers looking to use Clozapine effectively and efficiently in their practice.

Keywords

Clozapine

prescribing strategies

psychosis treatment

ANC monitoring

Clozapine REMS program

communication in care coordination