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Adherence to Antipsychotics in Schizophrenia: Clinical Considerations

Activity Type:

  • Webinar

Release Date: 2/25/2019

Expiration Date: 4/8/2019

  • AMA PRA Category 1: 1
  • Participation: 1


Event Details

The live presentation will take place on March 8, 2019, 12:00-1:00pm ET.

Advance registration is encouraged. Registrants will receive an event reminder by email one day prior to the webinar.


Poor adherence to antipsychotics is a critical prognostic factor for patients with schizophrenia. Good illness insight, while helpful, is neither necessary nor sufficient for good antipsychotic adherence. Psychiatrists need to competently estimate the degree of adherence in order to devise appropriate interventions. A good adherence assessment inquires about attitude (towards drugs), barriers, and (actual) compliance behavior. “Drug attitude” can be viewed as a final common pathway that sums up a patient’s subjective risk-benefit assessment of a medication; it includes medication efficacy, particularly its ability to reduce perceived suffering. Adherence is unlikely if drug attitude is not good. Clinical adherence-enhancing interventions can be grouped into universal (for all patients), selected (for patients at high risk for non-adherence) or indicated interventions (for currently non-adherent patients). Among the various interventions, long-acting injectable antipsychotics are an underused first-line treatment for schizophrenia patients who require maintenance treatment.

This webinar will emphasize how to comprehensively assess adherence using the ABCs of adherence (i.e., drug attitude, barriers, and compliance behavior) and how to optimize adherence based on the reasons for non-adherence. The appropriate use of long-acting injectable antipsychotics will be highlighted.


FREE - $0

Funding for this initiative was made possible (in part) by Grant No. 1H79SM080818-01 from SAMHSA. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. 

Learning Objectives

  • List four important risk factors for non-adherence to antipsychotics
  • Estimate adherence by inquiring about drug attitude, barriers, and compliance behavior
  • Develop a patient-specific treatment plan to optimize adherence

Target Audience

Psychiatrist, Nurse/Nurse Practitioner

Instructional Level


Estimated Time to Complete

Estimated Duration: 1.0 hours 
Program Start Date: March 8, 2019 
Program End Date: March 8, 2019 

Continuing Education Credit

Participants who wish to earn AMA PRA Category 1 Credit™, ANCC Contact Hours, or a certificate of participation may do so by attending the live presentation and completing the evaluation. After evaluating the program, course participants will be provided with an opportunity to claim hours of participation and print an official CME certificate (physicians), CNE certificate (nursing), or certificate of participation (non-physicians) showing the event date and hours earned.

Faculty and Planner Disclosures


  • Oliver Freudenrech, MD, FACLP, Co-Director, Massachusetts General Hospital Schizophrenia Clinical and Research Program. Reports no financial relationships with commercial interests. 


  • Tristan Gorrindo, MD, Director of Education, American Psychiatric Association. Reports no financial relationships with commercial interests. 
  • Donna Rolin, PhD, APRN. Clinical Associate Professor and Director of the Psychiatric Nurse Practitioner program, School of Nursing, University of Texas, Austin. Reports no financial relationships with commercial interests.
  • Alexander S. Young, MD, MSHS, Professor, Department of Psychiatry, UCLA; Director of Health Services, VA Mental Illness Research, Education and Clinical Center; Senior Scientist, RAND.  Reports no financial relationships with commercial interests.

Accessibility for Participants with Disabilities

The American Psychiatric Association is committed to ensuring accessibility of its website to people with disabilities.  Please contact the American Psychiatric Association at 202-559-3900, if you require assistance seven (7) days prior to the start of a live webinar.

Hardware/Software Requirements

We recommend that prior to the webinar, you check system requirements to ensure your device is compatible and rule out connectivity issuess.

This internet-based CME activity is best experienced using Internet Explorer 8+, Mozilla Firefox 3+, Safari 4+. This website requires that JavaScript and session cookies be enabled. Certain activities may require additional software to view multimedia, presentation, or printable versions of the content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Flash, Adobe Acrobat, Microsoft PowerPoint, and Windows Media Player.

Optimal System Configuration

  • Flash Player: Adobe Flash Player 10.3+ 
  • Browser: Firefox (latest version), Internet Explorer 8.0+, Safari 7.0+, Microsoft Edge (latest version) or Google Chrome (latest version)
  • Operating System: Windows XP+ or Mac OS X 10.4+ 
  • Internet Connection: 1 Mbps or higher

Minimum Requirements

  • Windows PC: 500-MHz Pentium II; Windows XP or higher; 128 MB RAM; Video Card at least 64MB of video memory; Macromedia Flash Player 10.3 or higher; Sound Card at least 16-bit; audio playback with speakers for programs with video content
  • Macintosh:Mac OS X 10.4+ or higher with latest updates installed; 1.83MHz Intel Core Duo or faster; RAM: 128MB or more; Video Card: at least 64MB of video memory; Sound Card: at least 16-bit; audio playback with speakers for programs with video content

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